Previous Releases

Note: CellProfiler versions 2.2 and 3.0 require installation of a Java 8 JDK

CellProfiler 4

Notes for 4.2.7 release:

MacOS notes:
Supports both Intel and ARM
We have received reports that CellProfiler stops working after upgrading to OS 14 (Sonoma). We are working to trace and resolve the issue, but we have anecdotal evidence that a re-install of CellProfiler may help.
Note 1: On Mac, after downloading, put CellProfiler in your Applications folder and ctrl-click (or right-click) and choose Open. Otherwise, you will receive a warning: “CellProfiler can’t be opened because it is from an unidentified developer”.
Note 2: Ignore the warning “Error loading pipeline file” - just click OK.

Windows notes:
On Windows, after downloading and launching CellProfiler, if you get the “Windows protected your PC” message, click “More info” to allow you to hit “Run anyway” to install.
Windows users encountering errors with the MeasureImageQuality module should download update KB4598291 from Microsoft, available here. 
If CellProfiler won't open, you may need to install the Visual C++ Redistributable available at this link. 
 

Note that 4.2.6 and 4.2.5 are functionally equivalent. 4.2.4 was briefly available as CellProfiler - 4.2.3; the two are functionally equivalent

Mac Notes: 

We're aware that some users are having trouble opening CellProfiler on the latest Mac OSX security patch. We're working on resolving this, in the meantime you may want to build from source (see below).

Additionally, some users have reported experiencing issues when opening CellProfiler since updating to macOS 10.15.7. While we are still investigating the problem, we have found a couple of workarounds to successfully open CellProfiler, which you can find here.

Note 1: On Mac, after downloading, put CellProfiler in your Applications folder and ctrl-click (or right-click) and choose Open. Otherwise, you will receive a warning: “CellProfiler can’t be opened because it is from an unidentified developer”.

Note 2: Ignore the warning “Error loading pipeline file” - just click OK.

PC Notes: On Windows, after downloading and launching CellProfiler, if you get the “Windows protected your PC” message, click “More info” to allow you to hit “Run anyway” to install.

Windows users encountering errors with the MeasureImageQuality module should download update KB4598291 from Microsoft, available here. 

If CellProfiler will not open, you may need to install the Visual C++ Redistributable available at this link. 

CellProfiler 3

CellProfiler 2

CellProfiler 1