Previous Releases

Note: CellProfiler versions 2.2 and 3.0 require installation of a Java 8 JDK

CellProfiler 4

4.2.7   macOS (10.15+)       Windows (64-bit)
4.2.6    macOS (10.15+)       Windows (64-bit)
4.2.5   macOS (10.15+)       Windows (64-bit)
4.2.4    macOS (10.15+)       Windows (64-bit)
4.2.1   macOS (10.14+)       Windows (64-bit)
4.1.3   macOS (10.14+)       Windows (64-bit)
4.0.7   macOS (10.14+)       Windows (64-bit)

 

Notes for 4.2.7 release:

MacOS notes:
Supports both Intel and ARM
We have received reports that CellProfiler stops working after upgrading to OS 14 (Sonoma). We are working to trace and resolve the issue, but we have anecdotal evidence that a re-install of CellProfiler may help.
Note 1: On Mac, after downloading, put CellProfiler in your Applications folder and ctrl-click (or right-click) and choose Open. Otherwise, you will receive a warning: “CellProfiler can’t be opened because it is from an unidentified developer”.
Note 2: Ignore the warning “Error loading pipeline file” - just click OK.

Windows notes:
On Windows, after downloading and launching CellProfiler, if you get the “Windows protected your PC” message, click “More info” to allow you to hit “Run anyway” to install.
Windows users encountering errors with the MeasureImageQuality module should download update KB4598291 from Microsoft, available here. 
If CellProfiler won't open, you may need to install the Visual C++ Redistributable available at this link. 
 

Note that 4.2.6 and 4.2.5 are functionally equivalent. 4.2.4 was briefly available as CellProfiler - 4.2.3; the two are functionally equivalent

Mac Notes: 

We're aware that some users are having trouble opening CellProfiler on the latest Mac OSX security patch. We're working on resolving this, in the meantime you may want to build from source (see below).

Additionally, some users have reported experiencing issues when opening CellProfiler since updating to macOS 10.15.7. While we are still investigating the problem, we have found a couple of workarounds to successfully open CellProfiler, which you can find here.

Note 1: On Mac, after downloading, put CellProfiler in your Applications folder and ctrl-click (or right-click) and choose Open. Otherwise, you will receive a warning: “CellProfiler can’t be opened because it is from an unidentified developer”.

Note 2: Ignore the warning “Error loading pipeline file” - just click OK.


PC Notes: On Windows, after downloading and launching CellProfiler, if you get the “Windows protected your PC” message, click “More info” to allow you to hit “Run anyway” to install.

Windows users encountering errors with the MeasureImageQuality module should download update KB4598291 from Microsoft, available here

If CellProfiler will not open, you may need to install the Visual C++ Redistributable available at this link

CellProfiler 3

3.1.9   macOS       Windows (64-bit)
3.1.8   macOS       Windows (64-bit)
3.1.5   macOS       Windows (64-bit)
3.0.0   macOS       Windows (64-bit)

 

CellProfiler 2

2.2.0   macOS       Windows (64-bit)
2.1.1   macOS     Windows (32-bit) Windows (64-bit)
2.1.0   macOS     Windows (32-bit) Windows (64-bit)
2.0.11710   macOS     Windows (32-bit) Windows (64-bit)
2.0.10997   macOS     Windows (32-bit) Windows (64-bit)
2.0.10415   macOS     Windows (32-bit) Windows (64-bit)
2.0.10211   macOS     Windows (32-bit) Windows (64-bit)

 

CellProfiler 1

1.0.9717 Linux 32-bit (MCRInstaller for GNU Linux 32-bit)

Linux 64-bit (MCRInstaller for GNU Linux 64-bit)
PowerPC macOS (Note: r5811) (MCR 7.6 is bundled with CP) Intel macOSintosh OS X 10.4+ 32/64-bit [Download currently unavailable] (MCRInstaller: Intel32.dmg) CP Cluster: CellProfiler for cluster computing: Linux 64-bit (MCRInstaller for GNU Linux 64-bit)

Matlab Source (Requires MATLAB R2009+)
Windows XP 32-bit (MCRInstaller for XP32)

Windows Vista (32-bit) (MCRInstaller for Vista32)
Windows XP 64-bit (MCRInstaller for XP64)

Windows Vista 64-bit (MCRInstaller for Vista64)
1.0.5811 Bugfix (Branch 6027) Linux64 macOSPPC macOSIntel Matlab (Developer) WindowsXP (32-bit)

Windows Vista (32-bit)
WindowsXP (64-bit)

Windows Vista (64-bit)
1.0.5811   macOSPPC macOSIntel [Download currently unavailable] Matlab (Developer) WindowsXP (32-bit)

Windows Vista (32-bit)
WindowsXP (64-bit)

Windows Vista (64-bit)
1.0.5122 Linux macOSPPC macOSIntel Matlab (Developer) WindowsXP (32-bit)

Windows Vista (32-bit)
WindowsXP (64-bit)

Windows Vista (64-bit)
1.0.4942 Linux macOSPPC macOSIntel Matlab (Developer) WindowsXP (32-bit)

Windows Vista (32-bit)
WindowsXP (64-bit)

Windows Vista (64-bit)
1.0.4884 Linux macOSPPC macOSIntel Matlab (Developer) WindowsXP (32-bit)

Windows Vista (32-bit)
WindowsXP (64-bit)

Windows Vista (64-bit)
1.0.4828 Linux macOSPPC macOSIntel Matlab (Developer) WindowsXP (32-bit) WindowsXP (64-bit)
1.0.4818 Linux macOSPPC macOSIntel Matlab (Developer) WindowsXP (32-bit) WindowsXP (64-bit)
1.0.4684 Linux macOSPPC macOSIntel Matlab (Developer) WindowsXP (32-bit) WindowsXP (64-bit)
1.0.4666 Linux [Download currently unavailable] macOSPPC   Matlab (Developer) [Download currently unavailable] WindowsXP (32-bit) WindowsXP (64-bit)
1.0.4628 Linux macOSPPC   Matlab (Developer) WindowsXP (32-bit) WindowsXP (64-bit)
1.0.4553 Linux macOSPPC   Matlab (Developer) WindowsXP (32-bit) WindowsXP (64-bit)
1.0.4532 Linux macOSPPC   Matlab (Developer) WindowsXP (32-bit) WindowsXP (64-bit)
1.0.4303 Linux macOSPPC   Matlab (Developer WindowsXP (32-bit) WindowsXP (64-bit)
1.0.4299 Linux macOSPPC   Matlab (Developer) WindowsXP (32-bit) WindowsXP (64-bit)
1.0.3755 Linux macOSPPC   Matlab (Developer) WindowsXP (32-bit) WindowsXP (64-bit)
1.0.3544 Linux macOSPPC   Matlab (Developer) WindowsXP (32-bit) WindowsXP (64-bit)
1.0.3443   macOSPPC   Matlab (Developer) WindowsXP (32-bit) WindowsXP (64-bit)
1.0.3215   macOSPPC   Matlab (Developer) WindowsXP (32-bit)  
1.0   macOSPPC   Matlab (Developer) WindowsXP (32-bit)